Jordanian Report on SARS-CoV-2 and COVID-19.
Documented research papers, patents, and funding sources clearly demonstrate that Severe Acute Respiratory Syndrome Corona Virus # 2 (SARS-CoV-2) associated with the development of Corona Virus Disease first presenting in 2019 (CoViD-19) is the result of Gain-of-Function research with a less than 1 in 3-Trillion probability of the virus having occurred naturally without human intervention.
The resulting nucleotide base sequences have resulted in two significant problems that require separate attention and understanding.
I. The spike protein.
Within the spike protein proper are two regions of concern due to their specific capacity to cause prion diseases. The first is the HIV gp120 insertion first reported by Shi Zhengli as she attempted to increase viral infectivity through alteration of the HKU4 spike protein. HIV gp 120 is a well-established prion that is known to produce neurologic damage by inducing changes in proneurotrophin pro-brain-derived neurotrophic factor (proBDNF). This gp120 attachment is significant as it establishes cellular attachment of the virus via Neu5AC binding. This binding results in the virus being brought into apposition with the ACE2 receptor, initiating a series of receptor site activation through TMPRSS2, the furin (PRRA) cleavage site and finally neuropilin-1; the later being critical for activation of neurologic InflammoThrombotic Response (ITR).
The second prion site within the spike protein complex occurs near the regional binding domain responsible for attachment of the spike protein to the ACE2 receptor and is the result of alterations to the three-dimensional structure of the spike protein. These alterations follow from insertions of the PRRA (proline-arginine-arginine-alanine) and various HIV (human) and SIV (simian) inserts as well documented by Professor Luc Montagnier and colleagues.
Documented changes in proteins with resulting prion diseases in both humanized mice and rhesus macaques have demonstrated spongiform encephalopathy (aka mad cow disease) and Alzheimer’s disease. Such prion diseases are also well documented in cardiac and other disease states including the development of Amyloidosis.
II. The InflammoThrombotic Response (ITR).
Above and beyond the fundamental concerns of the spike protein remains the fundamental problems associated with the induction of the InflammoThrombotic Response (ITR) resulting from either poorly regulated or unregulated immunologic response to a variety of factors; including but not limited to infectious agents. This theory was first presented and established by myself in 1994 at the American Heart Association meetings.
Briefly explained, the attachment and replication of a virus such as SARS-CoV-2 induces immunologic responses through both major histocompatibility complexes I and II (MHC I; MHC II). Following activation of these complexes a series of cytokines, interleukins, growth factors, tissue necrosis factors, thrombotic factors. The result of these factors briefly shown in the following figure is the biochemical pathways that under proper control and regulation with both destroy infected cells and limit blood flow into and out of an infected region/tissue.
This inflammation and blood clotting (thrombosis) under normal circumstances effectively control spread of an infectious agent throughout the body, while starving off the infectious agent by depriving it of nutrients and preventing it’s spread.
However, in circumstances where the person is already experiencing ITR diseases; including but not limited to coronary artery disease, hypertension, diabetes mellitus, obesity, tumors, cerebral vascular disease, et cetera, the addition of yet another series of ITRs can produce an uncontrolled response yielding tissue wide damage. With SARS-CoV- 2, this can been seen as myocardial and pericardial diseases, hepatic and renal disease, cerebral vascular disease, peripheral vascular disease, testicular and ovarian disease, gastrointestinal disease, respiratory disease including but not limited to acute respiratory distress syndrome (ARDS), et cetera.
Early in the course of disease transmission, these comorbid ITR diseases were associated with increased deaths due to a failure to address the ITR. Consequently, major organ system failure was seen followed by death.
With the introduction of the drug vaccine biologics (DVBs; vaccines), encoding the SARS- CoV-2 Wuhan Hu-1 spike protein, injected individuals were not exposed to hundreds to thousands of viral particles following translation of the mRNA into spike proteins that are independently capable of eliciting the ITR; but rather, 13.1 billion following the use of the Pfizer and Moderna mRNA drug vaccine biologics, and 50 billion following the injection of Janssen and Astra Zeneca DNA drug vaccine biologics. This massive increase in the number of spike antigens being presented by MHC I and II produced an augmented ITR in individuals with competent immune systems responding to a significantly increased viral load. The ITR does not and has not required the presence of an entire virus to be activated and produce clinical complications.
In addition to the activated ITR following the DVBs, evaluation of immune response to the DVBs have demonstrated a blunting of interferon production, reduction in T-lymphocyte counts, reductions in T-helper 2 (Th2) cells critical for adaptive immune response and impairment in immune response to subsequent DVBs for influenza.
In addition to the above noted problems, the use of the DVBs focusing on the SARS-CoV-2 Wuhan Hu-1 spike protein, has resulted in pressure selection of the virus producing variants now capable of escaping immunity to the original Wuhan Hu-1 spike protein. The consequence has been pressure selection yielding continued decline in potential vaccine benefit, while continuing to demonstrate augmented ITRs.
Theory of Inflammation in pictures: theory_of_inflammation_explained.pages
I am available to provide further explanation and discussion under Oath.
I declare under penalty of perjury that the foregoing is true and correct to the best of my knowledge and is based upon published research and published patents. Executed on 9 March 2022.
Printed name: Richard M Fleming, PhD, MD, JD
On February 22, 2022, Dr. Richard M. Fleming addressed American Liberty Forum on the above topic. You can watch the video by clicking here. He made a lot of people mad because he dared to challenge the popular narratives and the popular personalities. I don't do popular and I don't tip toe through the tulips when so much is at stake. America is devolving into an unrecognizable country with little hope of returning to the good ol' days of pre-2019. Well, maybe they weren't so good after all, and maybe we really don't want to return. Nevertheless, we don't want to continue in this downward spiral of becoming a socialist/marxist, godless, nation of subjects obeying their masters (the elitist-globalists), losing our minds and our souls and the very essence of who we are. If we don't fight with the truth, they win and we lose. I dare you to watch the video. Pay attention to the caveat emptor (buyer beware) in my introductory remarks. Tell me where you think Dr. Fleming is mistaken.
About the Author:
Beth Biesel is the Editor of the americanlibertyforum.org "What's New" Blog
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